Table 2.
Mast cell-derived Chemokines
| Factor | Stimulus | Product (if not the protein) | Mast cell type(s) | References |
|---|---|---|---|---|
| CCL1 | IgE/Ag | mRNA | Mouse cell lines | 11 |
| IL-33 | Human PBMCs or CBMCs | 191 | ||
| IgE/Ag or IL-33 | mRNA | Mouse BMCMCs | 365, 366 | |
| IgE/Ag | Mouse liver-derived | 367 | ||
| IgE/Ag | Human skin | 365 | ||
| CCL2 | IgE/Ag | mRNA | Mouse cell lines | 11 |
| IgE/Ag or IL-33 | Mouse BMCMCs, Human skin | 192 | ||
| PMA/ionophore, IgE/anti-IgE, IL-1β | Human CBMCs | 190 | ||
| IL-33 | Human PBMC or CBMCs | 191 | ||
| Poly(I:C) | Human CBMCs | 368 | ||
| CCL3 | IgE/Ag | mRNA | Mouse cell lines | 11 |
| IgE/Ag | Mouse liver-derived | 367 | ||
| IL-33 | Mouse BMCMCs | 192 | ||
| IgG receptor crosslinking | Mouse BMCMCs | 360 | ||
| Anti-IgE | Human CBMCs | 369 | ||
| CCL4 | IgE/Ag | mRNA | Mouse cell lines | 11 |
| In vivo | Mouse skin | 370 | ||
| Poly(I:C) | Human CBMCs | 368 | ||
| Dengue virus + Anti-dengue Ab | Human CBMCs | 371 | ||
| RSV | Human CBMCs | 372 | ||
| CCL5 | Human skin | 373 | ||
| Dengue virus + Anti-dengue Ab | Human CBMCs | 371 | ||
| RSV | Human CBMCs | 372 | ||
| CCL7 | IgE/Ag | Mouse BMCMCs | 374 | |
| Anti-FcεRIα Ab | mRNA | Human PBMCs | 375 | |
| CCL8 | LPS | mRNA | Human PBMCs | 233 |
| IgE/Ag or PMA/ionophore | mRNA | Mouse cell lines | 376 | |
| CCL9 | IgE/Ag | Mouse liver-derived | 367 | |
| CCL11 | Human skin | 373 | ||
| CCL17 | IL-33 | Human PBMCs or CBMCs | 191 | |
| Anti-FcεRIα Ab | mRNA | Human PBMCs | 375 | |
| mRNA | Human skin | 377 | ||
| CCL20 | Anti-FcεRIα Ab | mRNA | Human PBMCs | 375 |
| P. aeruginosa | Human CBMCs | 363 | ||
| CCL22 | IL-33 | Human PBMCs or CBMCs | 191 | |
| Anti-FcεRIα Ab | mRNA | Human PBMCs | 375 | |
| mRNA | Human skin | 377 | ||
| human CXCL2 | Anti-IgE | Human skin | 378 | |
| IgG immune complexes | Human synovium-derived | 379 | ||
| Anti-IgE, SCF, Substance P, Compound 48/80 or A23187 | Human skin | 27 | ||
| LPS+SCF | Human PBMCs | 87 | ||
| mouse CXCL8 | Anti-IgE | mRNA | Rat PMCs | 108 |
| IL-33 | Human PBMC or CBMC | 191 | ||
| Poly(I:C) | Human CBMCs | 368 | ||
| Substance P or ionomycin | Human CBMCs | 380 | ||
| CXCL10 | Poly(I:C) | Human CBMCs | 368 | |
| RSV | Human CBMCs | 372 |
BMCMCs: Mouse bone marrow-derived cultured mast cells (these are reported by many groups as “BMMCs” – referring to “bone marrow-derived mast cells”, but we prefer BMCMCs to refer to such cells as this is more specific and emphasizes that the cells have been derived in vitro.
CBMCs: Human umbilical cord blood-derived mast cells.
PBMCs: Human peripheral blood-derived mast cells.
PMCs: Peritoneal mast cells (from mice or rats, as noted).
In the Product column: Detected product was the protein unless “mRNA” is listed, which indicates that the mRNA for that product was identified, but not yet the protein.
In the References column: Papers listed include first reports and/or those with key data.