Table 1.

Incidence of histopathological lesions in the kidney by degree of severity.

Treatment group	Vehicle	Cisplatin
Number examined	45	44
No degeneration/necrosis present	44	13
Degeneration (tubule)	1*	18
Minimal (grade 1)	1	15
Mild (grade 2)	–	3
Necrosis (tubule)	–	26
Minimal (grade 1)	–	17
Mild (grade 2)	–	9

Incidence (numbers of animals) that sustained each lesion for a given severity grade is indicated in the table. N = 45 vehicle-treated mice and N = 44 cisplatin-treated mice.

*Indicates finding occurred in vehicle group and is unrelated to cisplatin exposure.