Table 3. Cox proportional hazard regression models for prognostic factors of survival after diagnosis of BM.
Variables | Total N = 78 |
Univariate | Multivariate | ||
---|---|---|---|---|---|
p | p | HR | 95%CI | ||
Sex | 0.247 | 0.567 | 0.796 | 0.364–1.740 | |
Female | 37 | ||||
Male | 41 | ||||
Dx age (each one year older) | 0.032 | 0.010 | 1.036 | 1.009–1.064 | |
Smoking | 0.088 | 0.190 | 1.573 | 0.800–3.091 | |
No | 42 | ||||
Yes | 36 | ||||
Stage | |||||
IA | 11 | ||||
IB | 8 | 0.926 | 0.792 | 0.852 | 0.260–2.794 |
IIA | 4 | 0.288 | 0.209 | 2.605 | 0.584–11.616 |
IIB | 4 | 0.633 | 0.471 | 1.910 | 0.329–11.095 |
IIIA | 28 | 0.568 | 0.554 | 0.757 | 0.301–1.905 |
IIIB | 23 | 0.114 | 0.128 | 2.050 | 0.813–5.170 |
Tumor size | 0.367 | 0.609 | 0.827 | 0.398–1.716 | |
≤30mm | 35 | ||||
>30mm | 43 | ||||
EGFR mutation status 1 | 0.417 | 0.304 | 0.687 | 0.335–1.407 | |
Wild-type | 29 | ||||
Mutant | 49 | ||||
EGFR mutation status 2 | 0.095 | 0.192 | 0.598 | 0.276–1.294 | |
Wild-type | 29 | ||||
Exon 19 deletion | 18 | 0.118 | 0.139 | 0.486 | 0.187–1.265 |
Other mutations | 31 | 0.938 | 0.471 | 0.765 | 0.368–1.587 |
Radiation therapy | 0.157 | 0.422 | 0.513 | 0.100–2.619 | |
No | 22 | ||||
Yes | 56 |