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. 2018 Feb 15;13(2):e0192161. doi: 10.1371/journal.pone.0192161

Table 3. Cox proportional hazard regression models for prognostic factors of survival after diagnosis of BM.

Variables Total
N = 78
Univariate Multivariate
p p HR 95%CI
Sex 0.247 0.567 0.796 0.364–1.740
    Female 37
    Male 41
Dx age (each one year older) 0.032 0.010 1.036 1.009–1.064
Smoking 0.088 0.190 1.573 0.800–3.091
    No 42
    Yes 36
Stage
    IA 11
    IB 8 0.926 0.792 0.852 0.260–2.794
    IIA 4 0.288 0.209 2.605 0.584–11.616
    IIB 4 0.633 0.471 1.910 0.329–11.095
    IIIA 28 0.568 0.554 0.757 0.301–1.905
    IIIB 23 0.114 0.128 2.050 0.813–5.170
Tumor size 0.367 0.609 0.827 0.398–1.716
    ≤30mm 35
    >30mm 43
EGFR mutation status 1 0.417 0.304 0.687 0.335–1.407
    Wild-type 29
    Mutant 49
EGFR mutation status 2 0.095 0.192 0.598 0.276–1.294
    Wild-type 29
    Exon 19 deletion 18 0.118 0.139 0.486 0.187–1.265
    Other mutations 31 0.938 0.471 0.765 0.368–1.587
Radiation therapy 0.157 0.422 0.513 0.100–2.619
    No 22
    Yes 56