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. 2018 Feb 15;13(2):e0192606. doi: 10.1371/journal.pone.0192606

Table 3. Distribution of differentially methylated regions (DMRs).

Thousands of DMRs in the liver were associated with maternal diet. Low-fat offspring had more DMRs than high-fat offspring. There were more than twice as many DMRs on the X-chromosome when comparing between sexes than within sexes. HF = High-fat diet, LF = Low-fat diet, the first diet listed is maternal diet and the second diet is the offspring diet, N = 2 libraries of 5 mice each (10 mice total) per maternal-diet-offspring-diet-sex group.

Comparison Group p<0.05 p<0.01 p<0.001 DMRs in X (%)
Different diets HF-HF ♀ vs. LF-HF ♀ 34,844 1,701 232 79 (0.2%)
HF-LF ♀ vs. LF-LF ♀ 55,014 9,550 2,566 284 (0.5%)
HF-HF ♂ vs. LF-HF ♂ 40,437 2,262 258 28 (0.1%)
HF-LF ♂ vs. LF-LF ♂ 57,374 8,737 1,505 75 (0.1%)
Different sexes HF-HF ♀ vs. HF-HF ♂ 41,340 5,031 1,679 1,219 (3.0%)
HF-LF ♀ vs. HF-LF ♂ 66,447 14,571 4,533 1,278 (1.9%)
LF-HF ♀ vs. LF-HF ♂ 40,766 5,610 1,728 1,074 (2.6%)
LF-LF ♀ vs. LF-LF ♂ 54,304 10,201 3,048 1,185 (2.2%)