Table 5. Distribution of significant differentially methylated regions (DMRs) (p < 0.01) across the genome associated with maternal diet.

Values indicate the number of 500 base-pair windows overlapping each genomic region, with the percent of the total significant DMRs overlapping these regions in parentheses. As a comparison, the percentage of windows across the whole genome that overlap these genomic regions is listed, demonstrating how overrepresented the DMRs are in regulatory regions.

Region	High Fat Daughters	High Fat Sons	Low Fat Daughters	Low Fat Sons	Whole Genome
Enhancer	180 (10.6%)	259 (20.3%)	1,038 (10.9%)	1,024 (11.7%)	3.5%
CTCF Binding Site	102 (6.0%)	129 (10.1%)	450 (4.7%)	614 (7.0%)	1.7%
TF binding site	16 (0.9%)	16 (1.3%)	62 (0.6%)	93 (1.1%)	0.3%
Promoter Flanking Region	549 (32.3%)	637 (49.9%)	3,625 (38.0%)	2,729 (31.2%)	8.1%
Promoter	251 (14.7%)	311 (13.8%)	1,366 (14.3%)	1,393 (15.9%)	4.5%
Exon	395 (23.2%)	528 (23.4%)	2,651 (27.8%)	1,958 (22.4%)	7.5%
Intergenic	616 (36.2%)	807 (35.7%)	2,870 (30.0%)	3,037 (34.8%)	58.6%