Table 5. Distribution of significant differentially methylated regions (DMRs) (p < 0.01) across the genome associated with maternal diet.
Region | High Fat Daughters | High Fat Sons | Low Fat Daughters | Low Fat Sons | Whole Genome |
---|---|---|---|---|---|
Enhancer | 180 (10.6%) | 259 (20.3%) | 1,038 (10.9%) | 1,024 (11.7%) | 3.5% |
CTCF Binding Site | 102 (6.0%) | 129 (10.1%) | 450 (4.7%) | 614 (7.0%) | 1.7% |
TF binding site | 16 (0.9%) | 16 (1.3%) | 62 (0.6%) | 93 (1.1%) | 0.3% |
Promoter Flanking Region | 549 (32.3%) | 637 (49.9%) | 3,625 (38.0%) | 2,729 (31.2%) | 8.1% |
Promoter | 251 (14.7%) | 311 (13.8%) | 1,366 (14.3%) | 1,393 (15.9%) | 4.5% |
Exon | 395 (23.2%) | 528 (23.4%) | 2,651 (27.8%) | 1,958 (22.4%) | 7.5% |
Intergenic | 616 (36.2%) | 807 (35.7%) | 2,870 (30.0%) | 3,037 (34.8%) | 58.6% |