Table 1. Characteristics of the Acute Kidney Injury Group and the non-Acute Kidney Injury Group on admission.
| Variables | AKI, n = 43 Median (% or IQR) |
Non-AKI, n = 17 Median (% or IQR) |
P |
|---|---|---|---|
| Male | 24 (55.8%) | 15 (88.2%) | 0.019 |
| Diabetes | 5 (11.6%) | 0 (0%) | 0.309 |
| Hypertension | 12 (27.9%) | 1 (5.9%) | 0.086 |
| Obesity | 27 (62.8%) | 7 (41.2%) | 0.128 |
| Smoking | 29 (67.4%) | 8 (47.1%) | 0.143 |
| Fever before admission | 41 (95.3%) | 13 (76.5%) | 0.048 |
| Antibiotics before admission | 37 (86.0%) | 12 (70.6%) | 0.265 |
| Nephrotoxic drugs | 25 (58.1%) | 4 (23.5%) | 0.016 |
| PEEP level >10 (cm H2O) | 15 (34.8%) | 10 (5.9%) | 0.031 |
| Deceased | 17 (39.5%) | 2 (11.8%) | 0.037 |
| Age (years) | 45 (IQR, 38–52) | 49 (IQR, 39–56) | 0.431 |
| PSI score | 81 (IQR, 64–114) | 76 (IQR, 64–105) | 0.774 |
| APACHE II score | 14 (IQR, 10–18) | 12 (IQR, 8–16) | 0.243 |
| SOFA score | 7 (IQR, 4–10) | 5 (IQR, 3.5–9) | 0.204 |
| pH | 7.39 (IQR, 7.34–7.46) | 7.42 (IQR, 7.39–7.46) | 0.650 |
| PaO2 (mmHg) | 39 (IQR, 31–52) | 35 (IQR, 28–42) | 0.325 |
| pCO2 (mmHg) | 33 (IQR, 28–50) | 33 (IQR, 27–40) | 0.935 |
| HCO3 (mmol/L) | 22 (IQR, 18–26) | 25 (IQR, 22–26) | 0.118 |
| PaO2/FIO2 (mmHg) | 93 (IQR, 61–132) | 118 (IQR, 62–154) | 0.333 |
| Hemoglobin (g/dL) | 15 (IQR, 14–17) | 16 (IQR, 14–16.5) | 0.659 |
| Leucocytes (x109/L) | 7400 (IQR, 5800–11300) | 7900 (IQR, 5200–12600) | 0.799 |
| Platelets (x109/L) | 170 (IQR, 142–232) | 199 (IQR, 136.5–265.5) | 0.827 |
| Urea nitrogen (mg/dL) | 20 (IQR, 12–29) | 16 (IQR, 12–24.6) | 0.275 |
| Creatinine (mg/dL) | 1.0 (IQR, 0.95–1.73) | 1.0 (IQR, 0.97–1.46) | 0.264 |
| Albumin (g/L) | 2.74 (IQR, 2.1–3.0) | 2.88 (IQR, 2.64–3.25) | 0.272 |
| LDH (U/L) | 642 (IQR, 358–1091) | 567 (IQR, 325–769) | 0.827 |
| CPK (U/L) | 205 (IQR, 113–387) | 329 (IQR, 120–1719) | 0.513 |
| AST (U/L) | 73 (IQR, 40–120) | 74 (IQR, 49.5–108) | 0.827 |
| Procalcitonin ng/mL | 1.0 (IQR, 0.07.2.79) | 0.38 (IQR, 0.05–1.89) | 0.275 |
| C-Reactive Protein (mg/L) | 13.1 (IQR, 8.4–24.2) | 2.97 (IQR, 0.78–4.1) | 0.127 |
| Glucose (mg/dL) | 150 (IQR, 111–190) | 129 (IQR, 99.5–153.5) | 0.250 |
| CKD-EPI (mL/min/1.73 m2 bs) | 70 (IQR, 46.5–98) | 86 (IQR, 58–102) | 0.268 |
| Cockcroft-Gault (mL/min) | 90 (IQR, 55.40–120) | 98 (IQR, 73–113) | 0.724 |
| Hospitalization (days) | 29 (IQR, 14–50) | 20 (IQR, 12–27.5) | 0.081 |
| Mechanical ventilation (days) | 19.5 (IQR, 9.5–37.2) | 10 (IQR, 5.5–26) | 0.253 |
AKI, Acute kidney injury; IQR, Interquartile range; %, Percentage; PEEP, Positive end-expiratory pressure; PSI, Pneumonia Severity Index; APACHE II, Acute Physiology and Chronic Health Evaluation II; SOFA, Sequential Organ Failure Assessment; PaO2/FiO2, Pressure arterial oxygen/Fraction of inspired oxygen; LDH, Lactic dehydrogenase; CPK, Creatine phosphokinase; AST, Aspartate aminotransferase; CKD-EPI, Chronic Kidney Disease Epidemiology Collaboration; CKD-EPI is expressed in mL/min/1.73m2 body size.