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. 2018 Feb 15;13(2):e0192746. doi: 10.1371/journal.pone.0192746

Fig 3. KEGG enrichment analysis of pathways up- or down-regulated in murine aortae in response to cortisol.

Fig 3

Twenty KEGG pathways were identified as significantly enriched (at an unadjusted p-value of 0.05). Of these, 7 were enriched for up-regulated genes (red), and 13 for down-regulated genes (blue). Of the pathways down-regulated by cortisol 9/13 were associated with inflammatory or immune responses and 4 were associated with extracellular matrix or cytoskeletal function.