Table 4. Adjusted odds ratios for sarcopenia in 260 elderly patients with NDD-CKD (adjusted for overall diuretic use).
| Model 1a | Model 2ab | Model 3ac | ||||
|---|---|---|---|---|---|---|
| Adjusted OR | P-value | Adjusted OR | P-value | Adjusted OR | P-value | |
| (95% CI) | (95% CI) | (95% CI) | ||||
| Age (per increase of 1 year) | 1.14 (1.08–1.20) | <0.001 | 1.13 (1.08–1.20) | <0.001 | 1.14 (1.08–1.21) | <0.001 |
| Male gender (ref = female) | 2.36 (1.15–4.84) | 0.020 | 2.72 (1.29–5.75) | 0.009 | 2.66 (1.24–5.70) | 0.012 |
| BMI (per increase of 1 kg/m2) | 0.79 (0.71–0.89) | <0.001 | 0.75 (0.66–0.85) | <0.001 | 0.72 (0.63–0.82) | <0.001 |
| eGFRcr (per increase of 10 mL/min/1.73 m2) | 0.72 (0.55–0.93) | 0.012 | 0.83 (0.63–1.10) | 0.19 | 0.87 (0.65–1.15) | 0.32 |
| Overall diuretic use (ref = no) | 3.73 (1.63–8.56) | 0.002 | 3.08 (1.31–7.23) | 0.010 | ||
| Diabetes mellitus (ref = no) | 2.65 (1.21–5.79) | 0.014 | ||||
BMI, body mass index; CI, confidence interval; eGFRcr, creatinine-based estimated glomerular filtration rate; NDD-CKD, non-dialysis-dependent chronic kidney disease; OR, odds ratio.
a Model 1 adjusted for age, gender, BMI, and eGFRcr
b Model 2a adjusted for all variables in model 1 plus overall diuretic use
c Model 3a adjusted for all variables in model 2a plus diabetes mellitus