Table 6. Adjusted odds ratios for sarcopenia in 260 elderly patients with NDD-CKD (adjusted for CKD stage and overall diuretic use).
Model 4a | Model 5ab | Model 6ac | ||||
---|---|---|---|---|---|---|
Adjusted OR | P-value | Adjusted OR | P-value | Adjusted OR | P-value | |
(95% CI) | (95% CI) | (95% CI) | ||||
Age (per increase of 1 year) | 1.14 (1.08–1.20) | <0.001 | 1.14 (1.08–1.20) | <0.001 | 1.14 (1.08–1.21) | <0.001 |
Male gender (ref = female) | 2.33 (1.13–4.79) | 0.021 | 2.70 (1.28–5.73) | 0.009 | 2.62 (1.22–5.63) | 0.014 |
BMI (per increase of 1 kg/m2) | 0.79 (0.71–0.89) | <0.001 | 0.75 (0.66–0.85) | <0.001 | 0.72 (0.63–0.83) | <0.001 |
CKD stage (ref = CKD stage 5) | ||||||
CKD stage 4 | 0.54 (0.21–1.39) | 0.21 | 0.62 (0.23–1.67) | 0.35 | 0.74 (0.27–2.02) | 0.56 |
CKD stage 3b | 0.31 (0.12–0.82) | 0.019 | 0.48 (0.17–1.37) | 0.17 | 0.54 (0.19–1.56) | 0.26 |
CKD stage 3a | 0.29 (0.09–0.92) | 0.036 | 0.46 (0.14–1.57) | 0.22 | 0.58 (0.17–2.03) | 0.40 |
Overall diuretic use (ref = no) | 3.71 (1.61–8.53) | 0.002 | 3.00 (1.27–7.07) | 0.012 | ||
Diabetes mellitus (ref = no) | 2.69 (1.22–5.91) | 0.014 |
BMI, body mass index; CI, confidence interval; CKD, chronic kidney disease; eGFRcr, creatinine-based estimated glomerular filtration rate; NDD-CKD, non-dialysis-dependent chronic kidney disease; OR, odds ratio.
a Model 4 adjusted for age, gender, BMI, and CKD stage
b Model 5a adjusted for all variables in model 4 plus overall diuretic use
c Model 6a adjusted for all variables in model 5a plus diabetes mellitus