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. 2018 Feb 15;13(2):e0192990. doi: 10.1371/journal.pone.0192990

Table 6. Adjusted odds ratios for sarcopenia in 260 elderly patients with NDD-CKD (adjusted for CKD stage and overall diuretic use).

Model 4a Model 5ab Model 6ac
Adjusted OR P-value Adjusted OR P-value Adjusted OR P-value
(95% CI) (95% CI) (95% CI)
Age (per increase of 1 year) 1.14 (1.08–1.20) <0.001 1.14 (1.08–1.20) <0.001 1.14 (1.08–1.21) <0.001
Male gender (ref = female) 2.33 (1.13–4.79) 0.021 2.70 (1.28–5.73) 0.009 2.62 (1.22–5.63) 0.014
BMI (per increase of 1 kg/m2) 0.79 (0.71–0.89) <0.001 0.75 (0.66–0.85) <0.001 0.72 (0.63–0.83) <0.001
CKD stage (ref = CKD stage 5)
 CKD stage 4 0.54 (0.21–1.39) 0.21 0.62 (0.23–1.67) 0.35 0.74 (0.27–2.02) 0.56
 CKD stage 3b 0.31 (0.12–0.82) 0.019 0.48 (0.17–1.37) 0.17 0.54 (0.19–1.56) 0.26
 CKD stage 3a 0.29 (0.09–0.92) 0.036 0.46 (0.14–1.57) 0.22 0.58 (0.17–2.03) 0.40
Overall diuretic use (ref = no) 3.71 (1.61–8.53) 0.002 3.00 (1.27–7.07) 0.012
Diabetes mellitus (ref = no) 2.69 (1.22–5.91) 0.014

BMI, body mass index; CI, confidence interval; CKD, chronic kidney disease; eGFRcr, creatinine-based estimated glomerular filtration rate; NDD-CKD, non-dialysis-dependent chronic kidney disease; OR, odds ratio.

a Model 4 adjusted for age, gender, BMI, and CKD stage

b Model 5a adjusted for all variables in model 4 plus overall diuretic use

c Model 6a adjusted for all variables in model 5a plus diabetes mellitus