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. 2018 Feb 15;13(2):e0192986. doi: 10.1371/journal.pone.0192986

Fig 2. Phenotype of B subsets in whole blood of patients with severe periodontitis (SP) and controls (No Periodontitis).

Fig 2

A) The gating strategy used after doublet exclusion allows the characterisation eight different and distinct B cell subsets. B) Circulating B cell distribution reveals an increase in the switched memory B cells and a decrease in the mature B cells in the SP patients in comparison with the controls. p value is indicated when significant. Plasmablasts: PB; Transitional B cells: TR; CD5+ B cells: CD5+; double negative IgD-CD27- B cells: DN; switched memory B cells: SwM; unswitched memory B cells: USwM; mature B cells: Mature and naïve B cells: Naïve.