Fig 7. Temporal fluctuations in levels of fatty acyl molecules following DENV infection of mosquito midguts.

(A) The abundances of fatty acyls that have known functions in immunomodulation. (B) The abundances of free fatty acids and N-acylamides that have known functions in signaling and/or that are markers of malfunction in fatty acid oxidation are shown. The abundances of metabolites detected in DENV-infected samples is shown in red and uninfected samples in black. Individual sample pools are represented by circles and squares and technical replicates are dots with the same symbol. Asterisks (*) indicates a significantly different abundance between DENV-infected and uninfected samples (|log₂ fold change| ≥ 1, p < 0.05). Abbreviations: DHOME, dihydroxyoctadecenoic acid; Dehydrodinor-TXB2, dehydrodinor-oxothromboxadienoic acid; Epoxy-DHA, epoxydocosahexaenoic acid; HEPE, hydroxyeicosapentaenoate; HpOTrE, hydroperoxyoctadecatrienoic acid; PGD2-dihydroxypropanylamine, Prostaglandin D2-dihydroxypropanylamine and TriHOME, trihydroxyoctadecenoic acid.