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. 2017 Nov 9;9(5):5517–5528. doi: 10.18632/oncotarget.22342

Figure 1. The miR-17 family is overexpressed in MYC-driven human HCC tumors.

Figure 1

A. TCGA analysis of microRNA expression identifies six members of the miR-17 (miR-17, miR-20a, miR-20b, miR-93, miR-106a and miR 106b) in normal liver and human HCC tumor tissue. B. MiR-17 expression is higher in tumors of higher stage than lower stage HCC. C. Patients with tumors with higher versus lower miR-17 family expression had worse survival. D. MiR-17 expression is higher in tumors with MYC genomic amplification than in those with normal diploid MYC.