Skip to main content
. 2018 Jan 8;9(5):6478–6489. doi: 10.18632/oncotarget.24031

Figure 4. Focal CCDC26 amplifications.

Figure 4

Horizontal grey lines illustrate focal recurrent amplifications detected in 9 CBF AML genomes across the CCDC26 locus. The area inside the dotted lines represents the minimal amplified region shared by all patients. Major variants of CCDC26 mRNA are shown in black below the figure. Exons are indicated by boxes. The long transcript consists of four exons (from e1 to e4) and the short transcripts comprise 3 or 4 exons (from 1a to e4, more or less exon 2a). The arrow shows the retrovirus insertion site defined by Yin et al [37].