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. Author manuscript; available in PMC: 2018 Apr 23.
Published in final edited form as: Oncogene. 2017 Oct 23;37(7):944–952. doi: 10.1038/onc.2017.400

Figure 2. PAK and MEK inhibitors block effects of RAC1 on zebrafish embryonic development.

Figure 2

One-cell embryos were injected with mRNA encoding the indicated genes. 1 µM inhibitors were added to water between 4.5–5.5hpf, then removed and replaced with fresh water. Embryo morphology was scored at 12hpf by a blinded observer. A) Morphology at 12hpf. B) Quantitation of developmental abnormalities.