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. Author manuscript; available in PMC: 2019 Mar 1.
Published in final edited form as: Wiley Interdiscip Rev Dev Biol. 2017 Nov 8;7(2):10.1002/wdev.306. doi: 10.1002/wdev.306

Figure 4. Two models of generating diversity from RGPs.

Figure 4

A rich variety of neuronal subtypes can arise from either temporal fate restriction of a common pool of dividing RGPs (radial glial progenitors, Model 1) or via multiple distinct pools of fate-restricted RGPs that are spatially segregated or enter mitosis at different times during embryonic neurogenesis (Model 2). The changes in neuronal progeny density may arise from the depletion of RGPs (dotted line). IPC, intermediate progenitor cell; L, layer.