Table 5.
Uncertainty in measurement study on the 12 GEM PREMIER 4000 analyzers (G1–G12) at two levels. The results are presented in concentrations and as percentages. For [H+], pCO2, pO2, Na+, Cl-, K+ and Ca2+, assays were carried out on solutions A and B; for lactate, Hb and O2Hb, on solutions A and D.
|
[H+] nmol/L (%) |
pCO2 mmHg (%) |
pO2 mmHg (%) |
Na+ mmol/L (%) |
Cl- mmol/L (%) |
K+ mmol/L (%) |
Ca2+ mmol/L (%) |
Lactate mmol/L (%) |
Hb g/dL (%) |
O2Hb % (%) |
|||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Sol A | Sol B | Sol A | Sol B | Sol A | Sol B | Sol A | Sol B | Sol A | Sol B | Sol A | Sol B | Sol A | Sol B | Sol A | Sol D | Sol A | Sol D | Sol A | Sol D | |
| G1 | 1.40 (1.14a) | 1.28 (3.28a) | 1.64 (2.49a) | 1.91 (5.60a) | 3.96 (3.54) | 9.45 (5.19) | 1.3 (1.2) | 2.3 (1.5) | 0.8 (1.6a) | 2.6 (3) | 0.16 (2.31a) | 0.17 (8.79) | 0.03 (1.55a) | 0.02 (3.04a) | 0.33 (9.85a) | 0.35 (4.29a) | 0.31 (2.16a) | 0.22 (3.03a) | 0.99 (1.11) | 1.99 (2.86) |
| G2 | 2.43 (1.97a) | 1.53 (3.94a) | 1.61 (2.44a) | 1.89 (5.56a) | 3.27 (2.95) | 9.27 (5.15) | 1.3 (1.3) | 1.9 (1.3) | 1.2 (2.5) | 1.6 (1.8a) | 0.10 (1.42a) | 0.01 (0.4a) | 0.05 (2.86a) | 0.02 (2a) | 0.19 (5.84a) | 0.41 (5.15a) | 0.25 (1.73a) | 0.22 (3.07a) | – | – |
| G3 | 2.15 (1.75a) | 1.51 (3.87a) | 1.99 (2.98a) | 1.91 (5.62a) | 5.43 (4.84) | 6.51 (3.60) | 1.2 (1.2) | 2.5 (1.6) | – | – | 0.11 (1.50a) | 0.01 (0.7a) | 0.04 (2.09a) | 0.02 (2a) | 0.18 (5.51a) | 0.37 (4.44a) | 0.19 (1.30a) | 0.31 (4.14a) | 1.27 (1.42) | 0.37 (0.53) |
| G4 | 4.52 (3.67a) | 1.27 (3.28a) | 2.44 (3.76a) | 1.92 (5.64a) | 3.32 (2.96) | 4.96 (2.75) | 0.9 (0.8a) | 2 (1.3) | – | – | 0.06 (0.86a) | 0.08 (4.14a) | 0.03 (1.64a) | 0.02 (2.66a) | 0.19 (5.83a) | 0.38 (4.72a) | 0.65 (4.48a) | 0.23 (3.12a) | 1.83 (2.04) | 1.31 (1.88) |
| G5 | 3.56 (2.88a) | 1.34 (3.45a) | 1.93 (2.92a) | 2.10 (6.17) | 4.53 (4.08) | 5.30 (2.94) | 1.3 (1.2) | 2.6 (1.7) | – | – | 0.10 (1.42a) | 0.01 (0.6a) | 0.05 (2.90a) | 0.02 (2.75a) | 0.24 (7.23a) | 0.47 (5.91a) | 0.58 (4a) | 0.44 (5.96a) | 0.66 (0.74) | 0.39 (0.57) |
| G6 | 2.37 (1.93a) | 1.70 (4.37) | 1.59 (2.45a) | 1.92 (5.64a) | 7.69 (6.93) | 13.34 (7.41) | 1.2 (1.1a) | 1.7 (1.1a) | – | – | 0.07 (0.96a) | 0.07 (3.46a) | – | – | – | – | 0.45 (3.14a) | 0.14 (1.84a) | 1.50 (1.68) | 1.13 (1.63) |
| G7 | 1.68 (1.37a) | 1.17 (3.00a) | 2.38 (3.77a) | 1.60 (4.69a) | 5.64 (5.04) | 10.51 (5.84) | – | – | – | – | – | – | – | – | – | – | 0.24 (1.69a) | 0.23 (3.04a) | 1.73 (1.94) | 1.53 (2.20) |
| G8 | 2.31 (1.88a) | 1.29 (3.32a) | 1.95 (2.95a) | 1.94 (5.70a) | 7.53 (6.78) | 6.79 (3.73) | 0.8 (0.8a) | 1.9 (1.3) | – | – | 0.10 (1.38a) | 0.01 (0.60a) | – | – | 0.33 (9.88a) | 0.18 (2.25a) | 0.39 (2.68a) | 0.22 (3.03a) | 1.16 (1.29) | 1.48 (2.14) |
| G9 | 4.27 (3.47a) | 1.02 (2.61a) | 1.78 (2.74a) | 1.64 (4.83a) | 4.58 (4.13) | 8.34 (4.63) | – | – | – | – | – | – | – | – | 0.19 (5.83a) | 0.94 (11.57a) | 0.58 (4a) | 0.23 (3.14a) | 1.17 (1.31) | 0.38 (0.55) |
| G10 | 2.87 (2.32a) | 1.31 (3.35a) | 1.98 (3a) | 1.95 (5.70a) | 4.61 (4.11) | 6.28 (3.49) | 1.7 (1.6) | 2.9 (1.9) | – | – | 0.11 (1.49a) | 0.01 (0.4a) | 0.02 (1.37a) | 0.02 (3.04a) | 0.17 (4.99a) | 0.63 (7.75a) | 0.59 (4.06a) | 0.12 (1.55a) | 1.18 (1.32) | 0.96 (1.38) |
| G11 | 3.99 (3.25a) | 1.32 (3.38a) | 3.19 (4.91a) | 1.73 (5.10a) | 6.62 (5.96) | 13.67 (7.60) | 1.6 (1.5) | 2.4 (1.6) | – | – | 0.05 (0.74a) | 0.14 (7.50a) | 0.04 (2a) | 0.02 (2.5a) | 0.12 (3.60a) | 0.30 (3.73a) | 0.25 (1.72aa) | 0.13 (1.80a) | 0.81 (0.90) | 0.67 (0.96) |
| G12 | 3.25 (2.60a) | 1.33 (3.42a) | 2.04 (3.09a) | 1.85 (5.44a) | 4.29 (3.86) | 7.58 (4.19) | – | – | – | – | – | – | – | – | 0.17 (4.99a) | 0.88 (10.9a) | – | – | – | – |
| Mean | 2.90 (2.35) | 1.34 (3.44) | 2.04 (3.13) | 1.86 (5.47) | 5.13 (4.60) | 8.5 (4.71) | 1,3 (1.2) | 2,2 (1.5) | 1 (2.1) | 2.1 (2.4) | 0,10 (1.34) | 0,06 (3) | 0,04 (2.06) | 0,02 (2.57) | 0,21 (6.36) | 0,49 (6.07) | 0,41 (2.81) | 0,23 (3.07) | 1.23 (1.38) | 1.02 (1.47) |
| Ricos et al. specifications | (3.9) | (5.7) | – | (1.1) | (2.2) | (8.4) | (3.1) | (15.2) | (6.3) | – | ||||||||||
[H+]: proton concentration, pCO2: partial pressure of CO2, pO2: partial pressure of O2, Na+: sodium, K+: potassium, Cl-: chloride, Ca2+: calcium, Hb: hemoglobin, O2Hb: oxyhemoglobin.
a
Result meets desirable specifications of Ricos et al. [22].