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. 2018 Feb 11;20(3):233–243. doi: 10.1016/j.neo.2018.01.006

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© 2018 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Figure S1 — Related to Figure 1. Overexpression of epithelial wild-type FGFR1 synergizes with paracrine FGF10 to induce EMT. (A) Panoramic view of regenerated prostate tissues (H&E staining) derived from PrECs-control or PrECs-FGFR1 combined with GFP-UGSM or FGF10-UGSM. The highlighted areas are presented in Figure 1 with high magnification. Scale bar, 0.5 mm. (B) IHC staining of E-Cadherin (red)/vimentin (green)/DAPI (blue) and merged image of regenerated tissues derived from PrECs-control + FGF10-UGSM and PrECs-FGFR1 + FGF10-UGSM groups. High-magnification image shows tumorigenic cells coexpressing E-cadherin and vimentin. Scale bar, 100 μm.