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. 2018 Feb 15;8:3090. doi: 10.1038/s41598-018-21439-1

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Ixr1 and ribosome biogenesis. (A) Genes downregulated after Ixr1 depletion associated to rRNA transcription, rRNA processing or ribosome assembly. (B) Validation of Ixr1 regulation of the main genes from this process by qPCR (C) Expression levels of rRNAs and their precursors. Upper scheme, relative positions of the primers designed for qPCR quantitation of the rRNAs and precursors. Lower left-part: fold changes in rRNAs and precursors expression in ixr1∆ versus W303.