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. 2018 Feb 15;8:3124. doi: 10.1038/s41598-018-20435-9

Table 1.

Association results for the best SNPs within the genome-wide significant regions in meta-analyses of ANZRAG OAG and the endophenotypes. Effect sizes of these SNPs on OAG are presented in Table 2.

Chr SNP Risk allele P-value Analysis Meta-analysis heterogeneity P Nearest Genes
10 rs72815193 G 6.10 × 10−10 OAG + VCDR 0.31 MYOF and XRCC6P1
3 rs56962872 G 2.81 × 10−8 OAG + VCDR 0.51 LINC02052 and CRYGS
9 rs6478746 G 4.54 × 10−8 OAG + CA 0.44 LOC105376277 and LMX1B
1 rs148639588 T 3.53 × 10−8 OAG + CA 0.71 COL11A1

OAG, open-angle glaucoma; CA, cup area; VCDR, vertical cup to disk ratio.