Table 3.

Association of the new loci with OAG and each of the endophenotypes separately.

Chr	SNP	P-value OAG (ANZRAG)	P-value OAG (combined)*	P-value CA	P-value DA	P-value VCDR	P-value IOP	Nearest gene
10	rs4918865^	1.89 × 10−5	2.31 × 10−6	6.66 × 10−5	0.9062	2.10 × 10−5	0.3966	MYOF and XRCC6P1
3	rs56962872	2.91 × 10−5	3.03 × 10−7	0.000321	0.2832	0.000209	0.3793	LINC02052 and CRYGS
9	rs6478746	1.09 × 10−5	9.10 × 10−7	0.001659	0.6499	0.003575	0.03146	LOC105376277 and LMX1B
13	rs9530458	4.50 × 10−6	3.45 × 10−9	0.01305	0.2964	0.01631	0.04911	LMO7

^rs4918865 is in high LD with rs72815193, LD r² = 0.93; *Meta-analysis of OAG in ANZRAG and NEIGHBORHOOD data; OAG, open-angle glaucoma; CA, cup area; DA, disk area; VCDR, vertical cup to disk ratio; IOP, intraocular pressure.