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. 2018 Feb 15;9:694. doi: 10.1038/s41467-018-03078-2

Table 4.

Genomic predictors of sepsis mortality

Model name Direction of change in patients with mortality Genomic features
Duke Up (5 genes) TRIB1, CKS2, MKI67, POLD3, PLK1
Down (13 genes) TGFBI, LY86, CST3, CBFA2T3, RCBTB2, TST, CX3CR1, CD5, MTMR11, CLEC10A, EMR3, DHRS7B, CEACAM8
Sage LR Up (9 genes) CFD, DDIT4, DEFA4, IFI27, IL1R2, IL8, MAFF, OCLN, RGS1
Down (9 genes) AIM2, APH1A, CCR2, EIF5A, GSTM1, HIST1H3H, NT5E, RAB40B, VNN3
Sage RF Up (13 genes) B4GALT4, BPI, CD24, CEP55, CTSG, DDIT4, G0S2, MPO, MT1G, NDUFV2, PAM, PSMA6, SEPP1
Down (4 genes) ABCB4, CTSS, IKZF2, NT5E
Stanford Up (8 genes) DEFA4, CD163, PER1, RGS1, HIF1A, SEPP1, C11orf74, CIT
Down (4 genes) LY86, TST, OR52R1, KCNJ2