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. 2018 Feb 15;8:3075. doi: 10.1038/s41598-018-21380-3

Table 2.

Association between maternal PAHs exposure and the risk of CHDs.

PAHs exposure Cases Controls cOR(95%CI) aORb(95%CI)
No.(%) No.(%)
Any CHDs
   low 43(12.0) 62(23.0) Ref. Ref.
   high 314(88.0) 208(77.0) 2.177(1.421,3.335) 2.029(1.266,3.251)*
septal defects
   low 27(11.5) 62(23.0) Ref. Ref.
   high 208(88.5) 208(77.0) 2.296(1.405,3.752) 2.373(1.376,4.093)*
conotruncal heart defects
   low 16(10.0) 62(23.0) Ref. Ref.
   high 144(90.0) 208(77.0) 2.683(1.488,4.836) 2.349(1.250,4.416)*
right-sided obstructive malformations
   low 11(9.6) 62(23.0) Ref. Ref.
   high 103(90.4) 208(77.0) 2.791(1.409,5.528) 2.423(1.190,4.933)*
left-sided obstructive malformations
   low 7(9.7) 62(23.0) Ref. Ref.
   high 65(90.3) 208(77.0) 2.768(1.207,6.345) 2.662(1.085,6.529)*
anomalous pulmonary venous return
   low 5(7.8) 62(23.0) Ref. Ref.
   high 59(92.2) 208(77.0) 3.517(1.352,9.149) 2.962(1.068,8.212)*
other cardiac structural abnormalities
   low 11(10.8) 62(23.0) Ref. Ref.
   high 91(89.2) 208(77.0) 2.466(1.241,4.906) 2.327(1.129,4.795)*

cOR: crude odds ration; aOR: adjusted odds ration, adjusted for maternal age, gestational week, housing renovation, factory or landfill nearby, cooking at home, parental smoking or ETS exposure, maternal alcohol consumption, folic acid supplements.