Fig. 1.

Autoantibody to apolipoprotein A-1 IgG ELISA reading (cutoff 37%) in 27 patients with advanced chronic HCV before, during and after direct-acting anti-viral therapy, commenced at week 0. By week 12 all patients responded to antiviral treatment and were HCV RNA negative. a Results in HCV genotype 1 patients, 2/15 relapsed after end of therapy; b results in HCV genotype 3 patients, 1/12 relapsed. Closed black circles show autoantibody-positive patients at week 0, open circles show autoantibody negative patients at week 0, the broken dashed black line shows patients that changed from seropositive to seronegative and vice versa during sampling. Error bars show the standard deviation between replicate values. The thick dashed grey line indicates a positive AAA1 IgG response