We summarize the phase I bridging program to evaluate the safety, tolerability and pharmacokinetics (PK) of ALZ-801 in healthy volunteers. |
ALZ-801 is an orally available, valine-conjugated prodrug of tramiprosate with substantially improved PK properties and gastrointestinal tolerability compared with the parent compound. |
Oral ALZ-801 represents an advanced and markedly improved clinical candidate for the treatment of Alzheimer’s disease. |