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Chronic A61603 treatment reduced reactive oxygen species-dependent 4-hydroxynonenal (4-HNE). A: Western blot for detection of 4-HNE in right ventricular homogenates. B: pooled data showing that 4-HNE was increased in the bleomycin (Bleo) model and that this increase was prevented with chronic A61603 treatment. **P < 0.01.
