Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Molecular design of the small molecule for the selective alkylation of the T–T mismatched DNA. (A) The structure of Hoechst–AVP conjugate. (B) The structure of TAT–acridine conjugate 1 reported by Zimmerman. (C) The structure of VDAT–acridine conjugate 2 designed in this study. (D) The conceptual scheme of the T–T mismatched DNA alkylation. (E) The predicted complex between the ligand and T–T mismatched DNA. (F) The predicted complex between the ligand and U–U mismatched RNA.
