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. 2017 Nov 16;46(3):e15. doi: 10.1093/nar/gkx1115

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© The Author(s) 2017. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Figure 3. — Detection of miRNA-like sncRNAs. Differentially expressed sncRNAs (blue) from the extended annotation in the comparison between DICER1 knockout and control experiments in human HCT116 cell lines for (A) miRNAs, (B) snoRNAs and (C) tRNAs. The analyses for the knockout of DROSHA and XPO5 are available as Supplementary Figures. (D) Representation of a novel miRNA detected by SeRPeNT (depicted as a read profile) whose precursor is the lncRNA RP11–141B14.1 (depicted as a green line). Profiles for both replicates are included. (E) Secondary structure prediction of the predicted miRNA precursor by FOMmiR.