Table 5.
Inhibition of mitochondrial succinate dehydrogenase (SDH) activity by different SDHIs in field isolates of Z. tritici shown to be less sensitive to both fluopyram and isofetamid
| IC50 (μM) | RFb | |||||
|---|---|---|---|---|---|---|
| Bixafen | Fluopyram | Isofetamid | Bixafen | Fluopyram | Isofetamid | |
| Lyon 35 | 0.038 ± 0.011a | 9.672 ± 3.793 | > 32 | 1.2 | 80.4 | > 640 |
| Orleans 26 | 0.031 ± 0.01 | 3.603 ± 0.994 | > 32 | 0.9 | 30.0 | > 640 |
| R15‐46 | 0.044 ± 0.011 | 12.41 ± 1.322 | > 32 | 1.3 | 103.1 | > 640 |
| Lyon 14 | 0.049 ± 0.013 | 1.053 ± 0.094 | 0.827 ± 0.018 | 1.4 | 8.3 | 16.7 |
| Flu‐6 | 0.106 ± 0.017 | 14.76 ± 1.317 | > 32 | 3.2 | 122.7 | > 640 |
| MM20 | 0.031 ± 0.017 | 0.134 ± 0.067 | 0.046 ± 0.009 | 0.9 | 1.1 | 0.9 |
| IPO323 | 0.033 ± 0.017 | 0.12 ± 0.008 | 0.05 ± 0.002 | 1.0 | 1.0 | 1.0 |
a
Values ± SD are indicated as means of three independent experiments.
b
Values are indicated as ratio between means of IC50 (field isolates) and IC50 (IPO323).