Table 3. Top prostate cancer pairs sorted by the most pronounced Δρ (P < 10−5).
miRNA | KEGG ID | KEGG name | Δρ | ρ T | ρ N | size | targets | p.DIANA |
---|---|---|---|---|---|---|---|---|
hsa-mir-195 | 04360 | Axon guidance | −0.93 | −0.19 | 0.75 | 128 (129) | 16 (17) | 0.190 |
hsa-mir-195 | 04510 | Focal adhesion | 0.88 | 0.18 | −0.70 | 194 (200) | 30 (31) | 0.013 |
hsa-mir-195 | 05218 | Melanoma | 0.88 | 0.18 | −0.70 | 63 (71) | 16 (16) | 0.013 |
hsa-mir-1307 | 05410 | Hypertrophic cardiomyopathy (HCM) | 0.86 | 0.38 | −0.49 | 75 (83) | 0 (0) | NT |
hsa-mir-195 | 05217 | Basal cell carcinoma | −0.85 | −0.17 | 0.68 | 54 (55) | 10 (10) | 0.309 |
hsa-mir-1307 | 05414 | Dilated cardiomyopathy | −0.85 | −0.39 | 0.46 | 81 (90) | 0 (0) | NT |
hsa-mir-1307 | 04122 | Sulfur relay system | −0.85 | −0.23 | 0.62 | 10 (10) | 0 (0) | NT |
hsa-mir-200a | 03022 | Basal transcription factors | −0.84 | −0.17 | 0.68 | 35 (36) | 0 (0) | 0.999 |
hsa-mir-944 | 00982 | Drug metabolism - cytochrome P450 | −0.83 | −0.52 | 0.32 | 55 (73) | 0 (0) | NT |
hsa-mir-141 | 00592 | alpha-Linolenic acid metabolism | 0.83 | 0.42 | −0.42 | 16 (20) | 0 (0) | NT |
hsa-mir-195 | 04964 | Proximal tubule bicarbonate reclamation | 0.83 | 0.15 | −0.67 | 22 (23) | 3 (4) | 1 |
hsa-mir-195 | 04912 | GnRH signaling pathway | 0.83 | 0.13 | −0.70 | 92 (101) | 10 (10) | 0.399 |
hsa-mir-195 | 05414 | Dilated cardiomyopathy | 0.82 | 0.14 | −0.69 | 81 (90) | 5 (5) | 1 |
hsa-mir-195 | 04664 | Fc epsilon RI signaling pathway | 0.82 | 0.14 | −0.69 | 70 (79) | 10 (10) | 0.243 |
hsa-mir-195 | 05100 | Bacterial invasion of epithelial cells | 0.82 | 0.20 | −0.62 | 69 (70) | 5 (5) | 0.271 |
A total of 482 tumor samples and 52 normal samples were used to compute correlations.