Table 3.
Summary of all genes included in this study
| Gene name | KEGG number | Protein function |
|---|---|---|
| alr | K01775 | Alanine racemase |
| amiA,B,C | K01448 | N‐Acetylmuramoyl‐L‐alanine amidase |
| amiD | K11066 | N‐Acetylmuramoyl‐L‐alanine amidase |
| ampG | K08218 | MFS transporter, PAT family, beta‐lactamase induction signal transducer |
| ampH | K18988 | Serine‐type D‐Ala‐D‐Ala carboxypeptidase/endopeptidase |
| anmK | K09001 | Anhydro‐N‐acetylmuramic acid kinase |
| argD | K00821 | Acetylornithine/N‐succinyldiaminopimelate aminotransferase |
| asd | K00133 | Aspartate‐semialdehyde dehydrogenase |
| aspC | K10206 | Aspartate aminotransferase |
| bacA (uppP) | K06153 | Undecaprenyl‐diphosphatase |
| dacA | K01286 | DD‐Carboxypeptidase PBP5 |
| dacB | K07259 | DD‐Carboxy‐/endopeptidase PBP4 |
| dacC | K07258 | D‐Alanyl‐D‐alanine carboxypeptidase; penicillin‐binding protein 6a |
| dacD | K07258 | D‐Alanyl‐D‐alanine carboxypeptidase; penicillin‐binding protein 6b |
| dapA | K01714 | 4‐Hydroxy‐tetrahydrodipicolinate synthase |
| dapC (argD) | K14267 | N‐Succinyldiaminopimelate aminotransferase |
| dapD | K00674 | 2,3,4,5‐Tetrahydropyridine‐2‐carboxylate N‐succinyltransferase |
| dapE (msgB) | K01439 | Succinyl‐diaminopimelate desuccinylase |
| dapF | K01778 | Diaminopimelate epimerase |
| ddl | K01921 | D‐Alanine‐D‐alanine ligase |
| ftsA | K03590 | Cell division protein FtsA |
| ftsB | K05589 | Cell division protein FtsB |
| ftsE | K09812 | Cell division transport system ATP‐binding protein |
| ftsI (pbpB) | K03587 | Transpeptidase involved in septal peptidoglycan synthesis (DD‐transpeptidase) |
| ftsK (spoIIIE) | K03466 | DNA segregation ATPase |
| ftsL (divIC) | K03586 | Cell division protein FtsL |
| ftsN | K03591 | Cell division protein FtsN |
| ftsP (sufl) | K04753 | Suppressor of FtsI |
| ftsQ | K03589 | Cell division protein FtsQ |
| ftsW (rodA, spoVE) | K03588 | Cell division protein FtsW, SEDS protein |
| ftsX | K09811 | Cell division transport system permease protein |
| ftsZ | K03531 | Cell division protein FtsZ (tubulin homolog) |
| glmM | K03431 | Phosphoglucosamine mutase |
| glmS | K00820 | Glucosamine‐‐fructose‐6‐phosphate aminotransferase |
| glmU | K04042 | Bifunctional UDP‐N‐acetylglucosamine pyrophosphorylase / Glucosamine‐1‐phosphate N‐acetyltransferase |
| glyA | K00600 | Glycine hydroxymethyltransferase, SHMT |
| ldt (erfK, srfK) | K16291 | LD‐transpeptidase |
| lpxT (yeiU) | K19803 | Lipid A 1‐diphosphate synthase; undecaprenyl pyrophosphate:lipid A 1‐phosphate phosphotransferase |
| lysC (apk) | K00928 | Aspartate kinase |
| metC | K01760 | Cystathionine beta‐lyase |
| mepA | K07261 | Murein DD‐endopeptidase |
| mepH | K19303 | Murein DD‐endopeptidase |
| mepM | K19304 | Murein DD‐endopeptidase |
| mepS | K13694 | Murein DD‐endopeptidase |
| mltB | K08305 | Membrane‐bound lytic murein transglycosylase B |
| mltC | K08306 | Membrane‐bound lytic murein transglycosylase C |
| mltD | K08307 | Putative membrane‐bound lytic murein transglycosylase D |
| mltE | K08308 | Lytic murein endotransglycosylase E |
| mltF | K18691 | Membrane‐bound lytic transglycosylase F, murein hydrolase |
| mltG | K07082 | Endolytic murein transglycosylase, septation protein, ampicillin sensitivity |
| mraY | K01000 | Phospho‐N‐acetylmuramoyl‐pentapeptide‐transferase |
| mrcA (ponA) | K05366 | Penicillin‐binding protein 1A/PBP1A (glycosyltransferase/DD‐transpeptidase) |
| mrcB (ponB) | K05365 | Penicillin‐binding protein 1B/PBP1B (glycosyltransferase/DD‐transpeptidase) |
| mrdA (pbpA) | K05515 | Penicillin‐binding protein 2/PBP2 (DD‐transpeptidase) |
| mreB (mbl) | K03569 | Rod shape‐determining protein MreB and related proteins (actin homolog) |
| mreC | K03570 | Rod shape‐determining protein MreC |
| mreD | K03571 | Rod shape‐determining protein MreD |
| mtgA | K03814 | Monofunctional glycosyltransferase |
| murA (murZ) | K00790 | UDP‐N‐acetylglucosamine 1‐carboxyvinyltransferase |
| murB | K00075 | UDP‐N‐acetylpyrovoylglucosamine dehydrogenase |
| murC | K01924 | UDP‐N‐acetylmuramate‐L‐alanine ligase |
| murD | K01925 | UDP‐N‐acetylmuramoylalanine‐‐D‐glutamate ligase |
| murE | K01928 | UDP‐N‐acetylmuramoyl‐L‐alanyl‐D‐glutamate‐‐2,6‐diaminopimelate ligase |
| murF | K01929 | UDP‐N‐acetylmuramoyl‐tripeptide‐‐D‐alanyl‐D‐alanine ligase |
| murG | K02563 | UDP‐N‐acetylglucosamine‐‐N‐acetylmuramyl‐(pentapeptide) pyrophosphoryl‐undecaprenol N‐acetylglucosamine transferase |
| murI (glr) | K01776 | Glutamate racemase |
| murJ (mviN) | K03980 | Putative peptidoglycan lipid II flippase |
| nagK | K00884 | N‐acetylglucosamine kinase |
| nagZ | K01207 | Beta‐N‐acetylhexosaminidase |
| pbpC | K05367 | Penicillin‐binding protein 1C (glycosyltransferase/DD‐transpeptidase) |
| pbpG | K07262 | Serine‐type D‐Ala‐D‐Ala endopeptidase PBP7 |
| pgpB | K01096 | PAP2‐type phosphatidylglycerophosphatase / undecaprenyl‐diphosphate diphosphatase |
| rodA (mrdB) | K05837 | Rod shape determining protein RodA, hypothetical lipid II flippase and/or glycosyltransferase |
| rodZ (yfqA) | K15539 | Cytoskeleton‐associated protein |
| slt (mltE) | K08309 | Soluble lytic murein transglycosylase |
| uppS (yaeS) | K00806 | Undecaprenyl diphosphate synthase |
| ybjG (bcrC) | K19302 | PAP2‐type undecaprenyl‐diphosphate diphosphatase |