Table 2.
Best Responses
| Response Categorya | Response Rate | P c | ||||
|---|---|---|---|---|---|---|
| 5‐d Regimensb | 10‐d Regimen at 60 mg/m2 (n = 53) | Total (n = 103) | ||||
| 60 mg/m2 (n = 24) | 90 mg/m2 (n = 26) | Total (n = 50) | ||||
| CR, No. (%) | 2 (8.3) | 2 (7.7) | 4 (8.0) | 10 (18.9) | 14 (13.6) | .1515d |
| CRi, No. (%) | 1 (4.2) | 3 (11.5) | 4 (8.0) | 2 (3.8) | 6 (5.8) | NS |
| CRp, No. (%) | 0 | 0 | 0 | 4 (7.5) | 4 (3.9) | NS |
| CRc rate (CR + CRi + CRp) | ||||||
| No. (%) | 3 (12.5) | 5 (19.2) | 8 (16.0) | 16 (30.2) | 24 (23.3) | .1061d |
| 95% CI, % | 2.7‐32.4 | 6.6‐39.4 | 7.2‐29.1 | 18.3‐44.3 | 15.5‐32.7 | |
Abbreviations: CI, confidence interval; CR, complete response; CRc, composite complete response; CRi, complete response with incomplete blood count recovery; CRp, complete response with incomplete platelet recovery; d, day; NS, not significant.
a
Taken from the 2003 International Working Group acute myeloid leukemia response criteria.14
b
P for CR (60 vs 90 mg/m2), 1.00; P for CRc (60 vs 90 mg/m2), .704.
c
Comparing the 5‐day regimens (total) and the 10‐day regimen.
d
Fisher's exact 2‐sided Pr ≤ P.