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. 2017 Dec 18;46(3):1362–1374. doi: 10.1093/nar/gkx1256

Table 1. Dissociation time, Inline graphic, of the GTPase deficient cognate ternary complex and effective selectivity, Inline graphic, for different near-cognate codons with and without drugs.

No drug Paromomycin Gentamicin Neomycin
Dissociation time, Inline graphic(s) 2±0.1 26±1 130±4 320±15
Fold increase by drug 13±1 65±4 160±11
Inline graphic-value on CUC 1760±180 75 ± 10 17 ± 4 3.9 ± 0.6
Fold decrease by drug 23± 4 104± 27 451±84
Inline graphic-value on UCC 5900±970 420 ± 76 103 ± 20 30 ± 5
Fold decrease by drug 14± 4 57± 15 197± 46
Inline graphic-value on UUA 1200±190 111 ± 22 14.6 ± 0.8 9 ± 1.7
Fold decrease by drug 11± 3 82± 14 133± 33