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. 2017 Dec 11;62(2):1700315. doi: 10.1002/mnfr.201700315

Figure 1.

Figure 1

Study setup, body weight (BW) and body composition development over time. A) Schematic overview of the study setup. Briefly, litters were standardized to six pups per nest. In week 3, pups were stratified by BW and placed on a glucose or fructose diet (animals in these groups are GLU or FRU). In week 6, all animals were switched to the same high fat diet (HF; animals are referred to as GLU‐HF or FRU‐HF). Animals were tested in the indirect calorimetry (InCa) system in week 5 and week 14, an oral glucose tolerance test (OGTT) was performed in week 11. Animals were sacrificed in week 15. B) BW over the intervention period (week 3–6) and HF period (week 6–15) for males and C) females, D) fat mass (FM) for males and E) females, F) adiposity for males and G) females. Black symbols and lines represent GLU until week 6 and GLU‐HF from week 7 till week 15; open symbols and dotted lines represent FRU groups until week 6 and FRU‐HF groups from week 7 till week 15. Values represent mean± SD, n = 12 for males, n = 14 for females.