Table 3.
Liver and spleen volume in patients enrolled in the Gaucher Outcome Survey as of February 25, 2017 (N = 1209)
| All patientsn = 1209 | <18 years of agen = 153 | ≥18 years of agen = 1056 | ||||
|---|---|---|---|---|---|---|
| n | Median (IQR) | n | Median (IQR) | n | Median (IQR) | |
| Liver volume, MN | 501 | 1.0 (0.9–1.2) | 32 | 1.1 (1.0–1.4) | 469 | 1.0 (0.9–1.2) |
| UK | 42 | 0.8 (0.7–0.9) | 0 | – | 42 | 0.8 (0.7–0.9) |
| Israel | 324 | 1.1 (1.0–1.3) | 15 | 1.2 (1.0–1.4) | 309 | 1.1 (1.0–1.2) |
| US | 122 | 1.0 (0.8–1.1) | 17 | 1.1 (0.9–1.4) | 105 | 1.0 (0.8–1.1) |
| ROWa | 13 | 0.8 (0.5–0.9) | 0 | – | 13 | 0.8 (0.5–0.9) |
| Spleen volume, MNb | 405 | 6.1 (4.2–8.2) | 31 | 7.8 (4.6–10.7) | 374 | 6.1 (4.1–8.1) |
| UK | 27 | 2.7 (2.2–3.6) | 0 | – | 27 | 2.7 (2.2–3.6) |
| Israel | 267 | 7.2 (5.9–9.3) | 15 | 8.6 (8.0–13.8) | 252 | 7.1 (5.9–9.2) |
| US | 97 | 2.9 (2.0–4.6) | 15 | 4.6 (3.0–7.3) | 82 | 2.6 (1.9–4.3) |
| ROWa | 14 | 4.9 (3.6–5.4) | 1 | 8.6 (8.6–8.6) | 13 | 4.9 (3.6–5.4) |
Abbreviations: IQR, interquartile range; MN, multiples of normal.
a
Argentina, Brazil, France, Italy, Paraguay, Poland, Spain, and Russia.
b
Patients with an intact spleen only.