Fig. (1).

Mosaic aneuploidy model proposed by Sterkers 2011 and Sterkers 2017 [124, 125]. During mitosis, there is an asymmetric replication of chromosomes followed by unequal division of the duplicated chromosomes to the daughters’ cells. This process generates mosaic aneuploidies inside a Leishmania population. (A) Asymmetric division resulting in one diploid and one haploid cell, which happens when there is a failure in the duplication of a given chromosome. (B) Asymmetric division resulting in one diploid and one triploid cell, which happens when an extra copy of a chromosome is produced during mitosis.