Table 3. Risk of Mortality After Ischemic and Bleeding Events During the 21-Month Postrandomization Period.
Variable | Adjusted HR (95% CI) for Mortalitya |
---|---|
Ischemic events | |
MI not related to ST | 9.1 (6.1-13.6) |
Definite or probable ST | 14.6 (8.2-25.9) |
Ischemic stroke | 13.1 (7.2-23.8) |
Any MI, definite or probable ST, or ischemic stroke | 12.6 (9.0-17.6) |
Bleeding events | |
GUSTO moderate bleed | 8.0 (4.7-13.7) |
GUSTO severe bleed | 36.3 (23.3-56.6) |
GUSTO moderate or severe bleed | 18.1 (12.6-26.0) |
BARC 2, 3, or 5 bleed | 9.3 (6.6-13.1) |
BARC 2 or 3 bleed | 5.7 (3.8-8.4) |
BARC 3 or 5 bleed | 16.2 (11.2-23.5) |
BARC 2 bleed | 3.4 (1.9-6.1) |
BARC 3 bleed | 8.6 (5.5-13.4) |
Abbreviations: BARC, Bleeding Academic Research Consortium; GUSTO, Global Utilization of Streptokinase and Tissue Plasminogen Activator for Occluded Arteries; HR, hazard ratio; MI, myocardial infarction; ST, stent thrombosis.