Table 3. Statin Eligibility Comparison: 2016 USPSTF Grade B Recommendation vs 2013 ACC/AHA Recommendationa.
| Statistic | CAC Score >0 | P Value | CAC Score ≥100 | P Value | AAC Score >0 | P Value |
|---|---|---|---|---|---|---|
| Difference in C statistic | −0.01 (−0.03 to 0.004) | .12 | 0.007 (−0.02 to 0.03) | .58 | −0.04 (−0.05 to −0.02) | <.001 |
| NRI (CAC) | −0.03 (−0.06 to 0.007) | .14 | 0.01 (−0.04 to 0.06) | .59 | −0.08 (−0.11 to −0.04) | <.001 |
| Net % of individuals with CAC correctly reclassified by USPSTF (NRI CAC) | −14 | <.001 | −11 | <.001 | −15 | <.001 |
| Net % of individuals without CAC correctly reclassified by USPSTF (NRI No CAC) | 11 | <.001 | 13 | <.001 | 8 | <.001 |
Abbreviations: AAC, abdominal aortic calcium; ACC/AHA, American College of Cardiology/American Heart Association; CAC, coronary artery calcium score; NRI, net reclassification index; USPSTF, US Preventive Services Task Force.
a
Comparison of eligibility status was performed such that reclassification metrics and C statistics represent the improvement of 2016 USPSTF guidelines over 2013 ACC/AHA guidelines.