Table 4.
Comparison of FA composition in adipose tissue between patients with kidney stones and the control group.
FA (provided by percentage of total amount) | Patients (n=71) | Controls## (n=100) | P value | |
---|---|---|---|---|
Without MS* (n=48) | With MS# (n=23) | |||
Mean ± Standard deviation | ||||
C 18: 1×ω**9 | 40.79±7.52 | 43.77±4.61 | 22.71±3.69 |
*,#p=0.041 *,##;#,##p<0.0001 |
C 20: 1ω9 | 1.26±0.80 | 0.92±0.35 | 0.56±0.48 |
*,#p=0.199 *,##;#,##p<0.0001 |
C 18: 3ω3 | 0.22±0.17 | 0.21±0.13 | 1.12±0.54 |
*,#p=0.858 *,##;#,##p<0.0001 |
C 22: 5ω3 | 0.23±0.23 | 0.21±0.17 | 0.39±0.27 |
*,#p=0.941 *,##;#,##p<0.0001 |
Ratio of ω3/ω6 | 0.05±0.03 | 0.05±0.02 | 1.13±0.28 |
*,#p=0.912 *,##;#,##p<0.0001 |
Total SFA (C 14: 0 + C 16: 0 + C 18: 0) | 34.54±3.89 | 33.62±2.88 | 32.14±5.29 |
*,#p=1.0 *,##p=0.008 #,##p=0.518 |
Total MUFA | 51.04±4.93 | 52.30±3.91 | 26.19±4.27 |
*,#p=0.762 *,##;#,##p<0.0001 |
Total PUFA | 14.42±3.08 | 14.07±3.78 | 35.13±4.84 |
*,#p=1.0 *,##;#,##p<0.0001 |
Ratio of PUFA/SFA | 0.42±0.1 | 0.42±0.13 | 1.13±0.29 |
*,#p=1.0 *,##;#,##p<0.0001 |
∑***ω3 | 0.76±0.58 | 0.72±0.52 | 4.5±1.46 |
*,#p=1.0 *,##;#,##p<0.0001 |
∑ ω6 | 13.67±2.82 | 13.36±3.34 | 27.91±4.56 |
*,#p=1.0 *,##;#,##p<0.0001 |
C 14: 0 | 3.8±1.13 | 3.3±0.81 | 4.49±2.34 |
*,#p=1.0 *,##p=0.124 #,##p=0.029 |
C 16: 0 | 25.01±2.51 | 24.94±2.05 | 21.9±2.4 |
*,#p=1.0 *,##;#,##p<0.0001 |
C 18: 0 | 5.72±1.44 | 5.38±1.1 | 6.49±1.05 |
*,#p=0.709 *,###,##p<0.0001 |
C 16: 1ω7 | 6.23±2.41 | 5.03±1.65 | 3.48±0.99 |
*,#p=0.003 *,##;#,##p<0.0001 |
C 18: 2ω6 | 13.25±2.7 | 13.02±3.2 | 22.59±3.98 |
*,##p=1.0 *,##;#,##p<0.0001 |
C 20: 4ω6 | 0.42±0.3 | 0.34±0.23 | 5.33±1.11 |
*,#p=1.0 *,##;#,##p<0.0001 |
C 20: 5ω3 | 0.11±0.07 | 0.1±0.08 | 1.06±0.68 |
*,##p=1.0 *,##;#,##p<0.0001 |
C 22: 6ω3 | 0.19±0.15 | 0.19±0.17 | 1.92±0.73 |
*,#p=1.0 *,##;#,##p<0.0001 |
SFA – saturated fatty acids; MUFA – monounsaturated fatty acids; PUFA – polyunsaturated fatty acids; * – kidney stone patients without MS; # – kidney stone patients with MS; ## – control group; C 18: 1× – number of carbon atoms and double bonds; ω** – position of double bond between carbon atoms in the molecule; ∑*** – total sum.