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. 2018 Feb 7;38(6):1472–1481. doi: 10.1523/JNEUROSCI.2602-17.2017

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Copyright © 2018 Auger et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License Creative Commons Attribution 4.0 International, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

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Figure 5. — Connectivity analyses. A, Results of the gPPI analysis. RSC (right) had greater functional coupling with medial temporal lobe regions (PHC and hippocampus; left) for permanent imageable sentences. Activations are displayed on sagittal views of a single representative participant's structural MRI brain scan. The RSC gPPI activation is displayed at a whole-brain uncorrected threshold of p < 0.001, and the color bar indicates Z-scores associated with each voxel. The medial temporal lobe seed region is taken from the whole-brain univariate contrast of imageable sentences (categories 1–4) versus non-imageable sentences (categories 5 and 6) displayed at the whole-brain FWE-corrected threshold of p < 0.05, which is also displayed in Figure 3A. B, The dynamics of permanence-related interactions. Four models of RSC–MTL interactions were compared in a DCM analysis (bottom) with their corresponding exceedance probabilities (top). Model 3 was the winning model, suggesting RSC and MTL mutually modulated each other's activity when an imageable sentence involved something permanent, with input to the system coming through RSC.