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. 2018 Feb 7;38(6):1493–1510. doi: 10.1523/JNEUROSCI.1548-17.2017

Figure 5.

Figure 5.

Synapses without visible PSDs. A, A 15-nm-thick tomographic slice of an unidentified synapse imaged by cryo-ET only. B, C, A 15-nm-thick tomographic slice of an excitatory (B) and an inhibitory (C) synapse identified by cryo-CLEM superposed with the fluorescence image of colocalized PSD-95-EGFP and mCherry-gephyrin, respectively. A1–C1, Zoomed-in views of the boxed area in A–C respectively showing that no PSD structures are visible in these synapses.