Table 3.

Effects of threat and object/scene memory encoding on whole-brain activity as parametrically modulated by pupil dilation responses to the overlap image

Brain region	Cluster	Z-statistic	MNI peak coordinates (mm)			Voxels
			X	Y	Z
Scene memory
Conventional cortical alignment
Threat > neutral	—	—	—	—	—	—
Forgot > Remember	—	—	—	—	—	—
Left frontal operculum	3	3.67	−40	16	2	1450
Left insula	3	3.54	−38	8	−6
Left central opercular cortex	3	3.54	−38	8	8
Left frontal operculum	3	3.38	−38	18	8
Left inferior frontal gyrus	3	3.29	−62	26	12
Left central opercular cortex	3	3.29	−44	−6	8
Left angular gyrus/supramarginal gyrus	2	3.55	−56	−50	18	954
Left anterior supramarginal gyrus	2	3.34	−62	−28	34
Left middle temporal gyrus	2	3.26	−56	−52	8
Left posterior supramarginal gyrus	2	3.21	−60	−50	10
Left posterior supramarginal gyrus	2	3.21	−50	−48	12
Left posterior supramarginal gyrus	2	3.2	−58	−44	26
Right posterior supramarginal gyrus	1	3.6	62	−36	42	613
Right posterior supramarginal gyrus	1	3.36	62	−44	20
Right anterior supramarginal gyrus	1	3.28	60	−32	40
Right anterior supramarginal gyrus	1	3.22	66	−28	34
Right anterior supramarginal gyrus	1	3.2	62	−28	46
Right anterior supramarginal gyrus	1	3.2	62	−32	46
Threat (Remember > Forgot) − neutral (Remember > Forgot)
Left lingual gyrus/PHG	1	3.98	−14	−42	−6	1127
Left parahippocampal gyrus	1	3.84	−14	−40	−10
Right lingual gyrus/PHG	1	3.81	14	−40	−10
Left posterior hippocampus	1	3.39	−22	−34	−8
Right temporal occipital fusiform cortex	1	3.34	32	−56	−12
Right temporal occipital fusiform cortex	1	3.29	24	−58	−14
Brainstem alignment
Threat > neutral	—	—	—	—	—	—
Remember > Forgot	—	—	—	—	—	—
Threat (Remember > Forgot) − neutral (Remember > Forgot)
Left cerebellum	1	3.51	−14	−58	−28	718
Left cerebellum	1	3.46	4	−62	−30
Right cerebellum	1	3.4	8	−54	−28
Brainstem	1	3.39	−8	−34	−30
Right cerebellum	1	3.32	4	−70	−34
Brainstem	1	3.24	−12	−30	−30
Object memory
Conventional cortical alignment
Remember > Forgot
Right frontal pole	2	3.35	26	46	20	938
Right precentral gyrus	2	3.21	54	8	42
Right frontal pole	2	3.21	34	46	16
Right inferior frontal gyrus	2	3.18	56	14	32
Right frontal pole	2	3.16	30	46	14
Right frontal pole	2	3.08	32	50	24
Right occipital pole	1	3.5	10	−94	16	843
Right occipital pole	1	3.25	10	−98	18
Right precuneus cortex	1	3.1	8	−58	8
Left intracalcarine cortex	1	3.09	−6	−66	8
Right precuneus cortex	1	3.08	10	−58	16
Right superior lateral occipital cortex	1	3.06	16	−82	20
Threat (Remember > Forgot) − neutral (Remember > Forgot)
Right inferior lateral occipital cortex	1	3.39	36	−70	8	851
Right cerebellum	1	3.23	38	−60	−24
Right cerebellum	1	3.2	36	−58	−28
Superior lateral occipital cortex	1	3.15	40	−88	22
Right cerebellum	1	3.08	38	−64	−24
Right occipital fusiform gyrus	1	3.03	34	−62	−12
Brainstem alignment
Remember > Forgot	—	—	—	—	—	—
Threat (Remember > Forgot) − neutral (Remember > Forgot)	—	—	—	—	—	—

For brainstem alignment, results are only reported if clusters were centered upon voxels in brainstem or midbrain because this alignment procedure may lead to misalignment of higher subcortical and cortical structures.

H, Hemisphere; PHG, parahippocampal gyrus; TO, temporal occipital; R, remember; F, forgot.