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Arg-Gln dipeptide administered by gavage reduces vaso-obliteration in the OIR mouse model. Representative retinal flat mounts from FITC-dextran–perfused mice from (A) normoxic mouse pups (P17) n = 6, (B) ROP mouse pups treated with the vehicle (P17) n = 11 (P = 0.03), (C) dipeptide-treated pups (P17) n = 9 (P = 0.02). (D) Graphical representation of all results (n.d., not detected). The yellow lines delineate the areas of retinal vaso-obliteration in (B, C). Scale bar: 1 mm.
