Temperature |
Raise to 32oC on QC |
t(7) = 1.626, p = 0.148 |
Paired t test |
|
D-TC on QC at 32oC |
t(8) = −4.765, p = 0.00142 |
Paired t test |
Fig. 1D |
Holding at −40 mV and −90 mV on QC |
t(9) = −0.635, p = 0.541 |
Paired t test |
Fig. 2A |
Baseline QC (QC) |
F(3,15) = 0.805, p = 0.499 |
ANOVA |
Fig. 2A |
D-TC on QC |
|
Paired t test |
|
Control |
t(21) = −11.467, p = 1.67E-10 |
|
|
αCtxArIB |
t(8) = −10.814, p = 4.72E-6 |
|
|
Atropine |
t(4) = −8.102, p = 0.00126 |
|
|
α7KO |
t(19) = −7.316, p = 6.15E-7 |
|
Fig. 2B |
α-Ctx MI on QC |
F(2,6) = 9.787, p < 0.0001 |
ANOVA |
Fig. 3C |
D-TC on QC with CCh puff |
t(9) = −15.213, p = 9.98E-8 |
ANOVA |
Fig. 3G |
Effect of ACh |
|
ANOVA |
|
EPC |
F(1,8) = 72.463, p < 0.0001 |
|
|
mEPC |
F(1,8) = 184.117, p < 0.0001 |
|
|
QC |
F(1,8) = 0.267, p = 0.667 |
|
Fig. 3H |
Ctrl vs +ACh + atropine |
|
ANOVA |
|
EPC |
F(1,6) = 25.143 p < 0.0001 |
|
|
mEPC |
F(1,6) = 31.179, p ≤ 0.0001 |
|
|
QC |
F(1,6) = 0.026, p = 0.873 |
|
Fig. 3H |
Ctrl vs ACh + atropine + D-TC |
|
ANOVA |
|
EPC |
F(1,6) = 70.508, p ≤ 0.0001 |
|
|
mEPC |
F(1,6) = 269.432, p ≤ 0.0001 |
|
|
QC |
F(1,6) = 25.644, p ≤ 0.0001 |
|
Fig. 3H |
ACh + atropine vs ACh + atropine + D-TC |
|
ANOVA |
|
EPC |
F(1,6) = 10.924, p = 0.001 |
|
|
mEPC |
F(1,6) = 250.029, p ≤ 0.0001 |
|
|
QC |
F(1,6) = 25.644, p ≤ 0.0001 |
|
Fig. 4A |
Before vs vecuronium |
|
ANOVA |
|
EPC |
F(1,10) = 126.367, p < 0.0001 |
|
|
mEPC |
F(1,10) = 805.135, p < 0.0001 |
|
|
QC |
F(1,10) = 42.313, p < 0.0001 |
|
Fig. 4A |
Vecuronium vs washout |
|
ANOVA |
|
EPC |
F(1,10) = 54.36, p < 0.0001 |
|
|
mEPC |
F(1,10) = 596.527, p < 0.0001 |
|
|
QC |
F(1,10) = 27.124, p < 0.0001 |
|
Fig. 4B |
Before vs mecamylamine |
|
ANOVA |
|
EPC |
F(1,4) = 7.92, p = 0.006 |
|
|
mEPC |
F(1,4) = 338.71, p < 0.0001 |
|
|
QC |
F(1,4) = 54.659, p < 0.0001 |
|
Fig. 4B |
Mecamylamine vs washout |
|
ANOVA |
|
EPC |
F(1,4) = 10.835, p = 0.002 |
|
|
mEPC |
F(1,4) = 602.623, p < 0.0001 |
|
|
QC |
F(1,4) = 39.211, p < 0.0001 |
|
Fig. 4D |
Before vs succinylcholine |
|
ANOVA |
|
EPC |
F(1,8) = 273.314, p < 0.0001 |
|
|
mEPC |
F(1,8) = 493.958, p < 0.0001 |
|
|
QC |
F(1,8) = 0.528, p = 0.498 |
|
Fig. 4D |
Succinylcholine vs washout |
|
ANOVA |
|
EPC |
F(1,8) = 110.816, p < 0.0001 |
|
|
mEPC |
F(1,8) = 172.376, p < 0.0001 |
|
|
QC |
F(1,8) = 0.486, p < 0.487 |
|
Fig. 5B |
mEPC decay tau change by |
|
Paired t test |
|
BTX |
t(18) = 6.458, p = 4.48E-6 |
|
|
D-TC |
t(17) = 12.355, p = 1.35E-9 |
|
|
Gallamine (GT) |
t(9) = 5.825, p = 2.52E-4 |
|
|
Mecamylamine |
t(4) = 7.263, p = 0.00191 |
|
|
Vecuronium |
t(12) = 5.048, p = 2.85E-4 |
|
|
Succinylcholine |
t(11) = −1.956, p = 0.0790 |
|
|
ACh/CCh |
t(21) = 3.705, p = 0.0014 |
|
|
BTX vs ACh/CCh on decay tau |
t(38) = 4.197, p = 1.57E-4 |
t test |