McGready 2001.

Methods	RCT Trial duration: 17 months between April 1995 and September 1996.
Participants	Participants were women who were 3 to 7 months' pregnant. Participants were not screened at start for P. vivax.
Interventions	20% DEET added to Thanaka (popular local cosmetic) compared to Thanaka alone. Co‐intervention: none Treatment arms: ‐ Thanaka containing 20% DEET arm ‒ 449; and ‐ Thanaka arm ‒ 448.
Outcomes	‐ Participants with malaria parasitaemia confirmed through blood smears (P. falciparum andP. vivax); ‐ Adherence to regular usage of the intervention measured through self‐reporting; ‐ Anaemia; and ‐ Recorded adverse events.
Notes	The study was carried out in camps for displaced people of the Karen ethnic minority in endemic regions of Thailand. The project was funded by the Danish Bilharziasis Laboratory and was part of the Wellcome‒Mahidol University of Oxford Tropical Medicine Research Programme funded by the Wellcome Trust.
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	Not described
Allocation concealment (selection bias)	Unclear risk	Not described
Blinding of participants and personnel (performance bias) Parasitaemia	Low risk	Double‐blinded RCT, both personnel and participants were blinded to the intervention.
Blinding of participants and personnel (performance bias) Anaemia	Low risk	Double‐blinded RCT, both personnel and participants were blinded to the intervention.
Blinding of participants and personnel (performance bias) Compliance	Low risk	Double‐blinded RCT, both personnel and participants were blinded to the intervention.
Blinding of participants and personnel (performance bias) Adverse events	Low risk	Double‐blinded RCT, both personnel and participants were blinded to the intervention.
Blinding of outcome assessment (detection bias) Parasitaemia	Low risk	Double‐blinded RCT, both personnel and participants were blinded to the intervention.
Blinding of outcome assessment (detection bias) Compliance	Low risk	Double blinded RCT, both personnel and participants were blinded to the intervention.
Blinding of outcome assessment (detection bias) Adverse events	Low risk	Double‐blinded RCT, both personnel and participants were blinded to the intervention.
Blinding of outcome assessment (detection bias) Anaemia	Low risk	This is an objective outcome.
Incomplete outcome data (attrition bias) All outcomes	Low risk	Attrition between arms was similar, data was not reported in the published but retrieved through communication with the author.
Selective reporting (reporting bias)	Low risk	Reporting was not clear in the published article but data of events between treatment arms was sent to us after communicating with the author.
Other bias	Low risk	Baseline imbalance "Between April 1995 and September 1996, 897 pregnant women were enrolled in the study, 449 into the DET and thanaka group and 448 into the thanaka alone group with no difference in baseline characteristics"