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. 2016 Dec 7;11(5):610–620. doi: 10.1093/ecco-jcc/jjw189

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© European Crohn’s and Colitis Organisation 2016.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 5. — αE integrin expression by CD4+ T lymphocytes is associated with a Th17/Th1 phenotype, which is enhanced in ulcerative colitis. Ex-vivo colonic CD4+ T cells were stimulated and analysed by flow cytometry for dual cytokine production of IL-17A and IFNγ. [A] Representative two-colour FACS plots of IL-17A vs IFNγ for CD4+αE+, CD4+αE− cells. [B] Summary Tukey box plots of double positive IL-17A+IFNγ+ lymphocyte frequency and double negative IL-17A−IFNγ− lymphocyte frequency [n = 4 control subjects and n = 6 UC patients].