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Microphotographs of representative examples of IHC PD-L1 heterogeneity expression in TAICs in TMA lung cancer specimens. Positive membrane staining (brown) in macrophages (A) and lymphocytes (B) are shown with PD-L1 E1L3N, E1J2J, SP142, 28-8, 22C3, and SP263 clone. ×4 magnification and detail at ×200 magnification. IHC indicates immunohistochemistry; PD-L1, programmed cell death ligand 1; TAICs, tumor-associated inflammatory cells; TMA, tissue microarrays.
