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. 2017 Dec 15;96(50):e9332. doi: 10.1097/MD.0000000000009332

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Copyright © 2017 the Author(s). Published by Wolters Kluwer Health, Inc.

This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc-nd/4.0

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Glioma recurrence in a 62-year-old man with grade III glioma. Contrast-enhanced T1-weighted image illustrated a heterogeneously ring enhanced lesion in the right frontal lobe with a large area of edema 14 months after CCRT. ASL-CBF, DSC-CBF and DSC-CBV maps showed ring-shaped hyperperfusion in the contrast-enhancing lesion, suggesting predominant high-grade tumor recurrence, which was confirmed on histopathology. ASL-CBF = arterial spin labeling-cerebral blood flow, CCRT = concurrent chemoradiotherapy, DSC-CBF = dynamic susceptibility contrast- cerebral blood flow, DSC-CBV = dynamic susceptibility contrast-cerebral blood volume.