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. 2017 Dec 15;96(50):e9332. doi: 10.1097/MD.0000000000009332

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Copyright © 2017 the Author(s). Published by Wolters Kluwer Health, Inc.

This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc-nd/4.0

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Radiation necrosis in a 53-year-old woman with grade II glioma. Contrast-enhanced T1-weighted image showed a heterogeneously ring enhanced lesion in the left frontal lobe 26 months after CCRT. ASL-CBF, DSC-CBF, and DSC-CBV maps showed iso- or a little hypoperfusion in the contrast-enhancing lesion, highly suggesting radiation-induced necrosis. Reoperative histologic analysis confirmed the diagnosis. ASL-CBF = arterial spin labeling-cerebral blood flow, CCRT = concurrent chemoradiotherapy, DSC-CBF = dynamic susceptibility contrast-cerebral blood flow, DSC-CBV = dynamic susceptibility contrast-cerebral blood volume.