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. 2017 Sep 28;153(2):349–360. doi: 10.1016/j.chest.2017.09.026

Figure 3.

Figure 3

Longitudinal change (Δ) in percent predicted Dlco in patients with chronic ILD over 12 months. aIncludes only patients with baseline and 12-month Dlco (n = 188); patients unable to perform Dlco maneuver at 12 months were excluded. (A) When classifying patients according to clinical diagnosis, DlcoΔ did not significantly differ between IPF and CHP (P = .101) or between CTD-ILD and IPAF (P = .233). (B) When classifying patients according to phenotypic clusters, DlcoΔ did not differ between Clusters 1 and 3 (P = .223); however, DlcoΔ was significantly different between Clusters 2 and 4 (P < .0001). Time 0 = initial ILD classification. See Figure 1 and 2 legends for expansion of abbreviations.