TABLE 2.
Bi-variate meta-regression
| Sensitivity | FPR | ||||
|---|---|---|---|---|---|
| Co-variate | Included Studies [References] | OR (95% CI) | p-value | OR (95% CI) | p-value |
| Mean age (years) | 15 [15–29] | 4.17 (0.75, 23.03) | 0.194 | 0.51 (0.11, 2.49) | 0.315 |
| Native language (Non English vs. English) | 10 [15–19, 23–25, 27, 29] | 0.55 (0.05, 5.59) | 0.083 | 0.06 (0.01, 0.28) | 0.001* |
| ECoG bandwidth lower bound (Hz) | 15 [15–29] | 18.96 (0.13, 2783.28) | 0.317 | 0.04 (0.00, 3.43) | 0.398 |
| ECoG bandwidth upper bound (Hz) | 15 [15–29] | 4.75 (1.20, 18.73) | 0.078 | 0.73 (0.22, 2.35) | 0.054 |
| ESM maximum current (mA) | 15 [15–29] | 39.31 (4.02, 384.25) | 0.001* | 0.45 (0.03, 6.82) | 0.616 |
| ESM pulse duration (ms) | 12 [15–17, 19–21, 23–28] | 0.13 (0.01, 2.50) | 0.087 | 0.07 (0.01, 0.75) | 0.325 |
(Bivariate random effects models were fitted to the pairs of transformed sensitivities (Sensitivityt) and false positive rates (FPRt): (Sensitivityt, FPRt) = ax + b, where: a = slope, b = intercept, and x = the covariate.
The transformation used was: x ⟼ ta (x): = a log x – (2 – a) log (1 – x)
Note that for α = 1, the logit transformation results. Hence, the odds ratios [OR] were obtained by inverse logit transformation, and represent the proportional gain in sensitivity or FPR per unit change in the covariate, for continuous variables. CI confidence interval, ECoG electrocorticographic, ESM electrical stimulation mapping, *p ≤ 0.05)